Detalhe da pesquisa
1.
A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.
Cell
; 157(7): 1644-1656, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24949974
2.
A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions.
Proc Natl Acad Sci U S A
; 119(14): e2114397119, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35312342
3.
Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis.
J Biol Chem
; 299(10): 105229, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37690681
4.
Sequence basis for selectivity of ephrin-B2 ligand for Eph receptors and pathogenic henipavirus G glycoproteins.
J Virol
; 97(11): e0062123, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931130
5.
TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules.
Nat Chem Biol
; 18(8): 859-868, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35725941
6.
Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants.
Nat Chem Biol
; 18(3): 342-351, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35046611
7.
The substrate import mechanism of the human serotonin transporter.
Biophys J
; 121(5): 715-730, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35114149
8.
Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology.
PLoS Pathog
; 16(6): e1008647, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559251
9.
Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.
Proc Natl Acad Sci U S A
; 116(51): 25602-25613, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31796585
10.
ACE2-based decoy receptors for SARS coronavirus 2.
Proteins
; 89(9): 1065-1078, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33973262
11.
Computationally Designed ACE2 Decoy Receptor Binds SARS-CoV-2 Spike (S) Protein with Tight Nanomolar Affinity.
J Chem Inf Model
; 61(9): 4656-4669, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34427448
12.
Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits.
J Biol Chem
; 294(13): 4759-4774, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30723160
13.
Conformational Engineering of HIV-1 Env Based on Mutational Tolerance in the CD4 and PG16 Bound States.
J Virol
; 93(11)2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894475
14.
Deep mutagenesis in the study of COVID-19: a technical overview for the proteomics community.
Expert Rev Proteomics
; 17(9): 633-638, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084449
15.
Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning.
J Immunol
; 200(11): 3825-3839, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678950
16.
Structural and energetic basis of folded-protein transport by the FimD usher.
Nature
; 496(7444): 243-6, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23579681
17.
Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.
Neurobiol Dis
; 118: 76-93, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30008368
18.
Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex.
J Biol Chem
; 291(47): 24566-24578, 2016 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681597
19.
Intracellular delivery system for antibody-Peptide drug conjugates.
Mol Ther
; 23(5): 907-917, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25669432
20.
Machine Learning Guided Design of High-Affinity ACE2 Decoys for SARS-CoV-2 Neutralization.
J Phys Chem B
; 127(9): 1995-2001, 2023 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36827526